Metabolites and small molecules
SLU-PP-332
SLU-PP-332 is a synthetic small-molecule agonist of the estrogen-related receptors (ERRα, ERRβ and ERRγ), described in the literature as an exercise mimetic.
- TypeSmall molecule
- FormulaC18H14N2O2
- Average mass290.32 g/mol
- CAS303760-60-3
- Vesta listings1
Reference page for laboratory use · updated 2026-10-30
Overview
SLU-PP-332 at a glance
The compound has the formula C18H14N2O2 and the systematic name 4-hydroxy-N-[(E)-naphthalen-2-ylmethylideneamino]benzamide. Published work covers metabolic-syndrome models, chemical optimisation and in-vitro metabolism.
Recent analytical papers describe its in-vitro metabolites and LC-MS characterisation, which is a useful reference when verifying batch identity.
Structure
The molecule is an acylhydrazone with an E-configured C=N bond between a 4-hydroxybenzoyl group and a naphthyl group.
Identity
Identity data
| Name | SLU-PP-332 |
|---|---|
| Also written as | ERR agonist SLU-PP-332 |
| Type | Small molecule |
| Research area | Metabolites and small molecules |
| Molecular formula | C18H14N2O2 |
| Monoisotopic mass | 290.1055 Da |
| Average molecular weight | 290.32 g/mol |
| CAS number | 303760-60-3 |
| PubChem record | CID 5338394 |
The formula comes from the PubChem record; monoisotopic mass is calculated from the formula and the average mass uses standard atomic weights. Reference data retrieved on 2026-10-30. Compare these values with the batch certificate of analysis, using the compound identity file template.
Expected values
Mass spectrometry reference
Ions calculated from the monoisotopic mass 290.1055 Da. Use them to check an LC-MS result; for larger peptides the instrument usually reports a deconvoluted mass close to 290.3 Da instead.
| Ion | m/z |
|---|---|
| [M+H]+ | 291.1128 |
| [M+Na]+ | 313.0947 |
| [M+K]+ | 329.0687 |
Read the guide to average and monoisotopic mass for how these values are calculated.
Quality
Analytical notes for batch documents
- E/Z isomers of acylhydrazones may be separable by HPLC; the COA should show that the main peak is the E isomer.
- Expect [M+H]+ at m/z 291.11. The compound is not a peptide, so peptide-style ion series do not apply.
- The molecular weight of a vial of powder includes counter-ions and water; the share of the powder that is peptide is the net peptide content.
Vesta listings
SLU-PP-332 formats and prices
| Product | Per vial | SKU | Price per kit | Price per vial |
|---|---|---|---|---|
| SLU-PP-332 | 5 mg | PP332 | $67.16 | $6.72 |
Prices are per kit of 10 vials in US dollars. Shipping is paid by the customer and is shown in the cart. Volume savings of 5 %, 8 % and 10 % apply from $350.00, $600.00 and $1,000.00. See the full price list.
Published literature
Selected scientific literature
Bibliographic details were read from PubMed on 2026-10-30. The papers are listed for scientific reference; Vesta makes no claim about the use of its research materials in people or animals.
- A Synthetic ERR Agonist Alleviates Metabolic SyndromeBillon C, Schoepke E, Avdagic A et al. · J Pharmacol Exp Ther · 2024 · PMID 37739806
- In Vitro Metabolism and Analytical Characterization of SLU-PP-332 and SLU-PP-915: Novel Pan-ERR Agonists With Doping PotentialMöller T, Krug O, Thevis M et al. · Rapid Commun Mass Spectrom · 2026 · PMID 41588687
Questions
Frequently asked questions
What is SLU-PP-332?
SLU-PP-332 is a synthetic small-molecule agonist of the estrogen-related receptors (ERRα, ERRβ and ERRγ), described in the literature as an exercise mimetic.
What is the molecular weight of SLU-PP-332?
SLU-PP-332 has the formula C18H14N2O2, an average molecular weight of 290.32 g/mol and a monoisotopic mass of 290.1055 Da. A salt form, a different counter-ion or a metal complex changes the molecular weight printed on a certificate of analysis, so compare like with like.
How can I check the identity of a batch of SLU-PP-332?
Compare the intact mass measured by LC-MS with the expected values on this page, for example [M+Na]+ at m/z 313.0947. Confirm that one main HPLC peak carries that mass and that the batch code on the report matches the vial. The guides on mass spectrometry and on certificates of analysis explain each step.
Which SLU-PP-332 products does Vesta list?
Vesta lists 1 product for SLU-PP-332: 5 mg per vial in kits of 10 vials. Prices are shown per kit in US dollars, and shipping is paid by the customer.