GHRP-2
GHRP-2 (pralmorelin) is a synthetic hexapeptide, D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2, that acts as a ghrelin-receptor agonist.
- TypePeptide
- FormulaC45H55N9O6
- Average mass817.97 g/mol
- CAS158861-67-7
- Vesta listings3
Reference page for laboratory use · updated 2026-10-30
Overview
GHRP-2 at a glance
GHRP-2 belongs to the family of synthetic growth hormone-releasing peptides. Its pharmacology and metabolism are described in published studies, including LC-MS methods for its detection.
Vesta lists it as the acetate salt, which matters for the molecular weight on the batch documents.
Structure
It contains three unnatural residues (D-Ala, D-2-naphthylalanine, D-Phe) and a C-terminal amide. The calculated formula agrees with PubChem.
Identity
Identity data
| Name | GHRP-2 |
|---|---|
| Also written as | Pralmorelin, KP-102 |
| Type | Peptide |
| Research area | Growth hormone axis peptides |
| Molecular formula | C45H55N9O6 |
| Monoisotopic mass | 817.4275 Da |
| Average molecular weight | 817.97 g/mol |
| CAS number | 158861-67-7 |
| Sequence | Ala-2Nal-Ala-Trp-Phe-Lys-NH2 |
| PubChem record | CID 6918245 |
The formula was calculated independently from the written sequence and matches the PubChem record exactly. Reference data retrieved on 2026-10-30. Compare these values with the batch certificate of analysis, using the compound identity file template.
Expected values
Mass spectrometry reference
Ions calculated from the monoisotopic mass 817.4275 Da. Use them to check an LC-MS result; for larger peptides the instrument usually reports a deconvoluted mass close to 818.0 Da instead.
| Ion | m/z |
|---|---|
| [M+H]+ | 818.4348 |
| [M+2H]2+ | 409.7210 |
| [M+Na]+ | 840.4167 |
| [M+K]+ | 856.3907 |
Read the guide to average and monoisotopic mass for how these values are calculated.
Quality
Analytical notes for batch documents
- The values in the table are for the free peptide. An acetate salt adds about 60.05 Da per acetate counter-ion, so the molecular weight printed on a COA for the salt is higher.
- Net peptide content is lower than 100 % because counter-ions and water are part of the powder.
- Mass shifts to look for in this sequence: tryptophan oxidation (+15.995 Da).
- The molecular weight of a vial of powder includes counter-ions and water; the share of the powder that is peptide is the net peptide content.
Terms used on this page: Acetate salt, Peptide, Counter-ion, Net peptide content.
Vesta listings
GHRP-2 formats and prices
| Product | Per vial | SKU | Price per kit | Price per vial |
|---|---|---|---|---|
| GHRP-2 Acetate | 5 mg | G25 | $63.43 | $6.34 |
| GHRP-2 Acetate | 10 mg | G210 | $97.01 | $9.70 |
| GHRP-2 Acetate | 15 mg | G215 | $128.73 | $12.87 |
Prices are per kit of 10 vials in US dollars. Shipping is paid by the customer and is shown in the cart. Volume savings of 5 %, 8 % and 10 % apply from $350.00, $600.00 and $1,000.00. See the full price list.
Published literature
Selected scientific literature
Bibliographic details were read from PubMed on 2026-10-30. The papers are listed for scientific reference; Vesta makes no claim about the use of its research materials in people or animals.
- Pharmacological characteristics of KP-102 (GHRP-2), a potent growth hormone-releasing peptideDoi N, Hirotani C, Ukai K et al. · Arzneimittelforschung · 2004 · PMID 15646370
- Determination of growth hormone secretagogue pralmorelin (GHRP-2) and its metabolite in human urine by liquid chromatography/electrospray ionization tandem mass spectrometryOkano M, Sato M, Ikekita A et al. · Rapid Commun Mass Spectrom · 2010 · PMID 20552695
Questions
Frequently asked questions
What is GHRP-2?
GHRP-2 (pralmorelin) is a synthetic hexapeptide, D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2, that acts as a ghrelin-receptor agonist.
What is the molecular weight of GHRP-2?
GHRP-2 has the formula C45H55N9O6, an average molecular weight of 817.97 g/mol and a monoisotopic mass of 817.4275 Da. A salt form, a different counter-ion or a metal complex changes the molecular weight printed on a certificate of analysis, so compare like with like.
How can I check the identity of a batch of GHRP-2?
Compare the intact mass measured by LC-MS with the expected values on this page, for example [M+2H]2+ at m/z 409.7210. Confirm that one main HPLC peak carries that mass and that the batch code on the report matches the vial. The guides on mass spectrometry and on certificates of analysis explain each step.
Which GHRP-2 products does Vesta list?
Vesta lists 3 products for GHRP-2: 5 mg, 10 mg, 15 mg per vial in kits of 10 vials. Prices are shown per kit in US dollars, and shipping is paid by the customer.