Adamax
Adamax is a research peptide described in public sources as a synthetic analogue of Semax. The structure is not published by the supplier, so the figures on this page come from a public reference and must be confirmed against batch LC-MS data.
- TypePeptide analogue
- Formula (reported)C50H69N11O11S
- Average mass1032.21 g/mol
- Vesta listings2
Reference page for laboratory use · updated 2026-10-30
Overview
Adamax at a glance
Semax is a seven-residue peptide, Met-Glu-His-Phe-Pro-Gly-Pro, that combines the ACTH(4-7) sequence with a C-terminal Pro-Gly-Pro tail. Adamax is described as a Semax analogue with chemical changes at both ends: an acetyl group on the N-terminus and an adamantane-containing group on the C-terminus.
Adamantane is a rigid, compact hydrocarbon cage. Adding it makes a peptide more hydrophobic, so Adamax is expected to be retained longer than Semax on a reversed-phase column. It also removes the free N-terminal amine, which has consequences for some sequencing and labelling methods.
The reported formula is C50H69N11O11S, an average molecular weight of 1032.21 g/mol and a monoisotopic mass of 1031.4899 Da. It matches the Semax sequence, an N-terminal acetyl cap and a C-terminal 3-aminoadamantane-1-carboxamide group, which we checked by adding the parts together. It is not a registry-confirmed value.
A PubChem search under this name found no record, and a PubMed search found no paper describing the peptide when this page was prepared. Public descriptions also disagree about the exact C-terminal group, which is another reason to rely on the intact mass and fragmentation data of the batch you hold.
Structure
Reported structure: Ac-Met-Glu-His-Phe-Pro-Gly-Pro joined through an amide bond to 3-aminoadamantane-1-carboxamide. The N-terminus is acetylated and the C-terminus carries the adamantane group.
Identity
Identity data
| Name | Adamax |
|---|---|
| Also written as | Ac-MEHFPGP-adamantyl |
| Type | Peptide analogue |
| Research area | Neuropeptide-derived peptides |
| Reported molecular formula (unconfirmed) | C50H69N11O11S |
| Monoisotopic mass (from the reported formula) | 1031.4899 Da |
| Average molecular weight (from the reported formula) | 1032.21 g/mol |
The numbers are calculated from a reported formula from a public encyclopaedia entry, not confirmed by the supplier or by a chemical registry. We checked that the formula equals the Semax sequence plus an N-terminal acetyl group and a C-terminal 3-aminoadamantane-1-carboxamide group, but no registry confirms it, so test it against the intact mass of your batch. Reference data retrieved on 2026-10-30. Compare these values with the batch certificate of analysis, using the compound identity file template.
Expected values
Mass spectrometry reference
Ions calculated from the monoisotopic mass 1031.4899 Da. Use them to check an LC-MS result; for larger peptides the instrument usually reports a deconvoluted mass close to 1032.2 Da instead.
| Ion | m/z |
|---|---|
| [M+H]+ | 1032.4972 |
| [M+2H]2+ | 516.7522 |
| [M+Na]+ | 1054.4791 |
| [M+K]+ | 1070.4531 |
Read the guide to average and monoisotopic mass for how these values are calculated.
Quality
Analytical notes for batch documents
- Treat the formula and mass on this page as a hypothesis to test, not as a specification. If the intact mass differs from 1031.49 Da, the vial may contain a different structure.
- Ask the supplier for the structure drawing, the intact-mass LC-MS result and, ideally, an MS/MS fragment spectrum that supports the C-terminal assignment.
- The N-terminal acetyl group blocks the amine, so Edman degradation does not work on this peptide.
- Ask for the HPLC method gradient. Because the molecule is more hydrophobic than Semax, a purity method developed for short polar peptides may under-resolve late-eluting impurities.
- The molecular weight of a vial of powder includes counter-ions and water; the share of the powder that is peptide is the net peptide content.
Terms used on this page: Peptide, N-terminus, C-terminus, Monoisotopic mass, HPLC.
Vesta listings
Adamax formats and prices
Prices are per kit of 10 vials in US dollars. Shipping is paid by the customer and is shown in the cart. Volume savings of 5 %, 8 % and 10 % apply from $350.00, $600.00 and $1,000.00. See the full price list.
Questions
Frequently asked questions
What is Adamax?
Adamax is a research peptide described in public sources as a synthetic analogue of Semax. The structure is not published by the supplier, so the figures on this page come from a public reference and must be confirmed against batch LC-MS data.
What is the molecular weight of Adamax?
Adamax (reported formula, unconfirmed) has the formula C50H69N11O11S, an average molecular weight of 1032.21 g/mol and a monoisotopic mass of 1031.4899 Da. A salt form, a different counter-ion or a metal complex changes the molecular weight printed on a certificate of analysis, so compare like with like. The supplier does not publish a structure, so check the value against the LC-MS result for your batch.
How can I check the identity of a batch of Adamax?
Compare the intact mass measured by LC-MS with the expected values on this page, for example [M+2H]2+ at m/z 516.7522. Confirm that one main HPLC peak carries that mass and that the batch code on the report matches the vial. The guides on mass spectrometry and on certificates of analysis explain each step.
Which Adamax products does Vesta list?
Vesta lists 2 products for Adamax: 5 mg, 10 mg per vial in kits of 10 vials. Prices are shown per kit in US dollars, and shipping is paid by the customer.
Is Adamax the same as Semax?
No. Public sources describe Adamax as a Semax analogue with an N-terminal acetyl group and a C-terminal adamantane-containing group, so it is a different molecule with a different mass.
Does Adamax have a CAS number or a PubChem record?
No record was found under this name in PubChem when this page was prepared, and the peptide has no CAS number in the sources we checked. Identity therefore rests on the batch documents.