Selank
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) that is an analogue of the immunomodulatory peptide tuftsin.
- TypePeptide
- FormulaC33H57N11O9
- Average mass751.87 g/mol
- CAS129954-34-3
- Vesta listings3
Reference page for laboratory use · updated 2026-10-30
Overview
Selank at a glance
Tuftsin is Thr-Lys-Pro-Arg; Selank extends it with the stabilising Pro-Gly-Pro sequence. It was developed in Russia, and most of the published pharmacology is in rodent models.
Vesta also lists a blend of Semax and Selank.
Structure
Three proline residues make the molecule structurally rigid and resistant to some peptidases. The calculated formula matches PubChem exactly.
Identity
Identity data
| Name | Selank |
|---|---|
| Also written as | TP-7 |
| Type | Peptide |
| Research area | Neuropeptide-derived peptides |
| Molecular formula | C33H57N11O9 |
| Monoisotopic mass | 751.4341 Da |
| Average molecular weight | 751.87 g/mol |
| CAS number | 129954-34-3 |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| PubChem record | CID 11765600 |
The formula was calculated independently from the written sequence and matches the PubChem record exactly. Reference data retrieved on 2026-10-30. Compare these values with the batch certificate of analysis, using the compound identity file template.
Expected values
Mass spectrometry reference
Ions calculated from the monoisotopic mass 751.4341 Da. Use them to check an LC-MS result; for larger peptides the instrument usually reports a deconvoluted mass close to 751.9 Da instead.
| Ion | m/z |
|---|---|
| [M+H]+ | 752.4414 |
| [M+2H]2+ | 376.7243 |
| [M+Na]+ | 774.4233 |
| [M+K]+ | 790.3973 |
Read the guide to average and monoisotopic mass for how these values are calculated.
Quality
Analytical notes for batch documents
- The expected ion [M+H]+ is m/z 752.44. Doubly charged ions are also seen because of the two basic residues.
- Proline-rich peptides can show split HPLC peaks caused by cis/trans proline isomers; this is not necessarily an impurity.
- No residue in this sequence is especially prone to oxidation or deamidation, so most extra peaks are likely to be synthesis-related impurities or adducts.
- The molecular weight of a vial of powder includes counter-ions and water; the share of the powder that is peptide is the net peptide content.
Terms used on this page: HPLC.
Vesta listings
Selank formats and prices
Research blends that contain Selank
| Product | Per vial | SKU | Price per kit | Price per vial |
|---|---|---|---|---|
| Semax10mg+Selank10mg | 20 mg | XS20 | $160.45 | $16.04 |
Prices are per kit of 10 vials in US dollars. Shipping is paid by the customer and is shown in the cart. Volume savings of 5 %, 8 % and 10 % apply from $350.00, $600.00 and $1,000.00. See the full price list.
Published literature
Selected scientific literature
Bibliographic details were read from PubMed on 2026-10-30. The papers are listed for scientific reference; Vesta makes no claim about the use of its research materials in people or animals.
- Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in RatsKonstantinopolsky MA, Chernyakova IV, Kolik LG et al. · Bull Exp Biol Med · 2022 · PMID 36322304
- Functional Connectomic Approach to Studying Selank and Semax EffectsPanikratova YR, Lebedeva IS, Sokolov OY et al. · Dokl Biol Sci · 2020 · PMID 32342318
Questions
Frequently asked questions
What is Selank?
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) that is an analogue of the immunomodulatory peptide tuftsin.
What is the molecular weight of Selank?
Selank has the formula C33H57N11O9, an average molecular weight of 751.87 g/mol and a monoisotopic mass of 751.4341 Da. A salt form, a different counter-ion or a metal complex changes the molecular weight printed on a certificate of analysis, so compare like with like.
How can I check the identity of a batch of Selank?
Compare the intact mass measured by LC-MS with the expected values on this page, for example [M+2H]2+ at m/z 376.7243. Confirm that one main HPLC peak carries that mass and that the batch code on the report matches the vial. The guides on mass spectrometry and on certificates of analysis explain each step.
Which Selank products does Vesta list?
Vesta lists 3 products for Selank: 5 mg, 10 mg per vial in kits of 10 vials, plus 1 research blend that contain it. Prices are shown per kit in US dollars, and shipping is paid by the customer.